14:15 SC Heerenveen – AZ Alkmaar OVER 1.50 (Total goals over 1.50)
15:30 Sint-Truidense VV – KRC Genk OVER 1.50 (Total goals over 1.50)
16:00 Sivasspor – Beşiktaş OVER 1.50 (Total goals over 1.50)
16:00 Celta Vigo – Girona FC X2 (Away team to win or draw)
16:30 Feyenoord – FC Twente 1 (Home team to win)
16:30 Go Ahead Eagles – NEC Nijmegen X2 (Away team to win or draw)
17:00 Lorient – Le Havre X2 (Away team to win or draw)
17:00 Stade de Reims – Nantes 1 (Home team to win)
17:00 Hellas Verona – Frosinone OVER 2.0 (Total goals over 2.0)
18:00 Monza – Sassuolo X2 (Away team to win or draw)
18:00 KAS Eupen – Royal Antwerp FC 2 (Away team to win)
18:30 Anderlecht – Royale Union Saint-Gilloise X2 (Away team to win or draw)
20:30 Olympiacos – PAS Giannina 1 (Home team to win)
21:15 KV Mechelen – RWD Molenbeek 1 (Home team to win)
21:30 PAOK – Panathinaikos OVER 2.0 (Total goals over 2.0)
22:45 Fiorentina – Inter OVER 2.0 (Total goals over 2.0)
23:30 Arouca – Vizela OVER 2.0 (Total goals over 2.0)
ALL MATCHES IN EAST AFRICAN TIME (EAT)